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Large domains of heterochromatin direct the formation of short mitotic chromosome loops

During mitosis chromosomes reorganise into highly compact, rod-shaped forms, thought to consist of consecutive chromatin loops around a central protein scaffold. Condensin complexes are involved in chromatin compaction, but the contribution of other chromatin proteins, DNA sequence and histone modif...

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Detalles Bibliográficos
Autores principales: Fitz-James, Maximilian H, Tong, Pin, Pidoux, Alison L, Ozadam, Hakan, Yang, Liyan, White, Sharon A, Dekker, Job, Allshire, Robin C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515631/
https://www.ncbi.nlm.nih.gov/pubmed/32915140
http://dx.doi.org/10.7554/eLife.57212