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A 5′ UTR GGN repeat controls localisation and translation of a potassium leak channel mRNA through G-quadruplex formation

RNA G-quadruplexes (G4s) are secondary structures proposed to function as regulators of post-transcriptional mRNA localisation and translation. G4s within some neuronal mRNAs are known to control distal localisation and local translation, contributing to distinct local proteomes that facilitate the...

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Detalles Bibliográficos
Autores principales: Maltby, Connor J, Schofield, James P R, Houghton, Steven D, O’Kelly, Ita, Vargas-Caballero, Mariana, Deinhardt, Katrin, Coldwell, Mark J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515701/
https://www.ncbi.nlm.nih.gov/pubmed/32870280
http://dx.doi.org/10.1093/nar/gkaa699