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Enhancer RNAs predict enhancer–gene regulatory links and are critical for enhancer function in neuronal systems
Genomic enhancer elements regulate gene expression programs important for neuronal fate and function and are implicated in brain disease states. Enhancers undergo bidirectional transcription to generate non-coding enhancer RNAs (eRNAs). However, eRNA function remains controversial. Here, we combined...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515708/ https://www.ncbi.nlm.nih.gov/pubmed/32810208 http://dx.doi.org/10.1093/nar/gkaa671 |