Enhancer RNAs predict enhancer–gene regulatory links and are critical for enhancer function in neuronal systems

Genomic enhancer elements regulate gene expression programs important for neuronal fate and function and are implicated in brain disease states. Enhancers undergo bidirectional transcription to generate non-coding enhancer RNAs (eRNAs). However, eRNA function remains controversial. Here, we combined...

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Detalles Bibliográficos
Autores principales: Carullo, Nancy V N, Phillips III, Robert A, Simon, Rhiana C, Soto, Salomon A Roman, Hinds, Jenna E, Salisbury, Aaron J, Revanna, Jasmin S, Bunner, Kendra D, Ianov, Lara, Sultan, Faraz A, Savell, Katherine E, Gersbach, Charles A, Day, Jeremy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515708/
https://www.ncbi.nlm.nih.gov/pubmed/32810208
http://dx.doi.org/10.1093/nar/gkaa671

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