Cargando…
ATM antagonizes NHEJ proteins assembly and DNA-ends synapsis at single-ended DNA double strand breaks
Two DNA repair pathways operate at DNA double strand breaks (DSBs): non-homologous end-joining (NHEJ), that requires two adjacent DNA ends for ligation, and homologous recombination (HR), that resects one DNA strand for invasion of a homologous duplex. Faithful repair of replicative single-ended DSB...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515714/ https://www.ncbi.nlm.nih.gov/pubmed/32890395 http://dx.doi.org/10.1093/nar/gkaa723 |