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SPRINT: a Cas13a-based platform for detection of small molecules

Recent efforts in biological engineering have made detection of nucleic acids in samples more rapid, inexpensive and sensitive using CRISPR-based approaches. We expand one of these Cas13a-based methods to detect small molecules in a one-batch assay. Using SHERLOCK-based profiling of in vitrotranscri...

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Detalles Bibliográficos
Autores principales: Iwasaki, Roman S, Batey, Robert T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515716/
https://www.ncbi.nlm.nih.gov/pubmed/32797156
http://dx.doi.org/10.1093/nar/gkaa673