A multiplexed bioluminescent reporter for sensitive and non-invasive tracking of DNA double strand break repair dynamics in vitro and in vivo

Tracking DNA double strand break (DSB) repair is paramount for the understanding and therapeutic development of various diseases including cancers. Herein, we describe a multiplexed bioluminescent repair reporter (BLRR) for non-invasive monitoring of DSB repair pathways in living cells and animals....

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Detalles Bibliográficos
Autores principales: Chien, Jasper Che-Yung, Tabet, Elie, Pinkham, Kelsey, da Hora, Cintia Carla, Chang, Jason Cheng-Yu, Lin, Steven, Badr, Christian E, Lai, Charles Pin-Kuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515717/
https://www.ncbi.nlm.nih.gov/pubmed/32797168
http://dx.doi.org/10.1093/nar/gkaa669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515717/
https://www.ncbi.nlm.nih.gov/pubmed/32797168
http://dx.doi.org/10.1093/nar/gkaa669

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