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Inferring efficiency of translation initiation and elongation from ribosome profiling
One of the main goals of ribosome profiling is to quantify the rate of protein synthesis at the level of translation. Here, we develop a method for inferring translation elongation kinetics from ribosome profiling data using recent advances in mathematical modelling of mRNA translation. Our method d...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515720/ https://www.ncbi.nlm.nih.gov/pubmed/32821926 http://dx.doi.org/10.1093/nar/gkaa678 |