Semisynthesis of site-specifically succinylated histone reveals that succinylation regulates nucleosome unwrapping rate and DNA accessibility

Posttranslational modifications (PTMs) of histones represent a crucial regulatory mechanism of nucleosome and chromatin dynamics in various of DNA-based cellular processes, such as replication, transcription and DNA damage repair. Lysine succinylation (Ksucc) is a newly identified histone PTM, but i...

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Detalles Bibliográficos
Autores principales: Jing, Yihang, Ding, Dongbo, Tian, Gaofei, Kwan, Ka Chun Jonathan, Liu, Zheng, Ishibashi, Toyotaka, Li, Xiang David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515725/
https://www.ncbi.nlm.nih.gov/pubmed/32766790
http://dx.doi.org/10.1093/nar/gkaa663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515725/
https://www.ncbi.nlm.nih.gov/pubmed/32766790
http://dx.doi.org/10.1093/nar/gkaa663

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