A role of the CTCF binding site at enhancer Eα in the dynamic chromatin organization of the Tcra–Tcrd locus

The regulation of T cell receptor Tcra gene rearrangement has been extensively studied. The enhancer Eα plays an essential role in Tcra rearrangement by establishing a recombination centre in the Jα array and a chromatin hub for interactions between Vα and Jα genes. But the mechanism of the Eα and i...

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Detalles Bibliográficos
Autores principales: Zhao, Hao, Li, Zhaoqiang, Zhu, Yongchang, Bian, Shasha, Zhang, Yan, Qin, Litao, Naik, Abani Kanta, He, Jiangtu, Zhang, Zhenhai, Krangel, Michael S, Hao, Bingtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515734/
https://www.ncbi.nlm.nih.gov/pubmed/32853367
http://dx.doi.org/10.1093/nar/gkaa711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515734/
https://www.ncbi.nlm.nih.gov/pubmed/32853367
http://dx.doi.org/10.1093/nar/gkaa711

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