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Spacer acquisition by Type III CRISPR–Cas system during bacteriophage infection of Thermus thermophilus

Type III CRISPR–Cas systems provide immunity to foreign DNA by targeting its transcripts. Target recognition activates RNases and DNases that may either destroy foreign DNA directly or elicit collateral damage inducing death of infected cells. While some Type III systems encode a reverse transcripta...

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Detalles Bibliográficos
Autores principales: Artamonova, Daria, Karneyeva, Karyna, Medvedeva, Sofia, Klimuk, Evgeny, Kolesnik, Matvey, Yasinskaya, Anna, Samolygo, Aleksei, Severinov, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515739/
https://www.ncbi.nlm.nih.gov/pubmed/32821943
http://dx.doi.org/10.1093/nar/gkaa685