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Spacer acquisition by Type III CRISPR–Cas system during bacteriophage infection of Thermus thermophilus
Type III CRISPR–Cas systems provide immunity to foreign DNA by targeting its transcripts. Target recognition activates RNases and DNases that may either destroy foreign DNA directly or elicit collateral damage inducing death of infected cells. While some Type III systems encode a reverse transcripta...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515739/ https://www.ncbi.nlm.nih.gov/pubmed/32821943 http://dx.doi.org/10.1093/nar/gkaa685 |