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HKDC1 C-terminal based peptides inhibit extranodal natural killer/T-cell lymphoma by modulation of mitochondrial function and EBV suppression

Extranodal nasal-type natural killer/T-cell lymphoma (ENKTL) is an Epstein–Barr virus (EBV) associated lymphoma that progresses rapidly and relapses frequently. Advanced ENKTL is multidrug chemoresistant and has a poor prognosis. In this study, we aim to develop a novel hexokinase domain component 1...

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Detalles Bibliográficos
Autores principales: Chen, Qi, Feng, Jia, Wu, Jinhu, Yu, Zhendong, Zhang, Wei, Chen, Yonggang, Yao, Paul, Zhang, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515829/
https://www.ncbi.nlm.nih.gov/pubmed/32203147
http://dx.doi.org/10.1038/s41375-020-0801-5