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Androgen receptor signaling regulates the transcriptome of prostate cancer cells by modulating global alternative splicing

Androgen receptor (AR), is a transcription factor and a member of a hormone receptor superfamily. AR plays a vital role in the progression of prostate cancer and is a crucial target for therapeutic interventions. While the majority of advanced-stage prostate cancer patients will initially respond to...

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Detalles Bibliográficos
Autores principales: Shah, Kalpit, Gagliano, Teresa, Garland, Lisa, O’Hanlon, Timothy, Bortolotti, Daria, Gentili, Valentina, Rizzo, Roberta, Giamas, Georgios, Dean, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515832/
https://www.ncbi.nlm.nih.gov/pubmed/32820253
http://dx.doi.org/10.1038/s41388-020-01429-2