MiR-450a-5p strengthens the drug sensitivity of gefitinib in glioma chemotherapy via regulating autophagy by targeting EGFR

Glioma reported to be refractory to EGFR tyrosine kinase inhibitor is the most common malignant tumor in central nervous system. Our research showed the low expression of miR-450a-5p and high expression of EGFR in glioma tissues. MiR-450a-5p was also observed to synergize with gefitinib to inhibit t...

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Detalles Bibliográficos
Autores principales: Liu, Yu, Yang, Liang, Liao, Fan, Wang, Wei, Wang, Zhi-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515841/
https://www.ncbi.nlm.nih.gov/pubmed/32820249
http://dx.doi.org/10.1038/s41388-020-01422-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515841/
https://www.ncbi.nlm.nih.gov/pubmed/32820249
http://dx.doi.org/10.1038/s41388-020-01422-9

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