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Blood biomarkers indicate that the preclinical stages of Alzheimer's disease present overlapping molecular features

It is still debated whether non-specific preclinical symptoms of Alzheimer’s disease (AD) can have diagnostic relevance. We followed the evolution from cognitively normal to AD by NMR-based metabolomics of blood sera. Multivariate statistical analysis of the NMR profiles yielded models that discrimi...

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Detalles Bibliográficos
Autores principales: Di Costanzo, Alfonso, Paris, Debora, Melck, Dominique, Angiolillo, Antonella, Corso, Gaetano, Maniscalco, Mauro, Motta, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515866/
https://www.ncbi.nlm.nih.gov/pubmed/32973179
http://dx.doi.org/10.1038/s41598-020-71832-y