Comparative genomics of Alexander Fleming’s original Penicillium isolate (IMI 15378) reveals sequence divergence of penicillin synthesis genes

Antibiotics were derived originally from wild organisms and therefore understanding how these compounds evolve among different lineages might help with the design of new antimicrobial drugs. We report the draft genome sequence of Alexander Fleming’s original fungal isolate behind the discovery of pe...

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Detalles Bibliográficos
Autores principales: Pathak, Ayush, Nowell, Reuben W., Wilson, Christopher G., Ryan, Matthew J., Barraclough, Timothy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515868/
https://www.ncbi.nlm.nih.gov/pubmed/32973216
http://dx.doi.org/10.1038/s41598-020-72584-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515868/
https://www.ncbi.nlm.nih.gov/pubmed/32973216
http://dx.doi.org/10.1038/s41598-020-72584-5

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