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Kir3 channel blockade in the cerebellar cortex suppresses performance of classically conditioned Purkinje cell responses

In the eyeblink conditioning paradigm, cerebellar Purkinje cells learn to respond to the conditional stimulus with an adaptively timed pause in its spontaneous firing. Evidence suggests that the pause is elicited by glutamate released from parallel fibers and acting on metabotropic receptors (mGluR7...

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Detalles Bibliográficos
Autores principales: Johansson, Fredrik, Hesslow, Germund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515874/
https://www.ncbi.nlm.nih.gov/pubmed/32973240
http://dx.doi.org/10.1038/s41598-020-72581-8