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Kir3 channel blockade in the cerebellar cortex suppresses performance of classically conditioned Purkinje cell responses
In the eyeblink conditioning paradigm, cerebellar Purkinje cells learn to respond to the conditional stimulus with an adaptively timed pause in its spontaneous firing. Evidence suggests that the pause is elicited by glutamate released from parallel fibers and acting on metabotropic receptors (mGluR7...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515874/ https://www.ncbi.nlm.nih.gov/pubmed/32973240 http://dx.doi.org/10.1038/s41598-020-72581-8 |