Topical ripasudil stimulates neuroprotection and axon regeneration in adult mice following optic nerve injury

Optic nerve injury induces optic nerve degeneration and retinal ganglion cell (RGC) death that lead to visual disturbance. In this study, we examined if topical ripasudil has therapeutic potential in adult mice after optic nerve crush (ONC). Topical ripasudil suppressed ONC-induced phosphorylation o...

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Detalles Bibliográficos
Autores principales: Nishijima, Euido, Namekata, Kazuhiko, Kimura, Atsuko, Guo, Xiaoli, Harada, Chikako, Noro, Takahiko, Nakano, Tadashi, Harada, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515881/
https://www.ncbi.nlm.nih.gov/pubmed/32973242
http://dx.doi.org/10.1038/s41598-020-72748-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515881/
https://www.ncbi.nlm.nih.gov/pubmed/32973242
http://dx.doi.org/10.1038/s41598-020-72748-3

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