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Topical ripasudil stimulates neuroprotection and axon regeneration in adult mice following optic nerve injury
Optic nerve injury induces optic nerve degeneration and retinal ganglion cell (RGC) death that lead to visual disturbance. In this study, we examined if topical ripasudil has therapeutic potential in adult mice after optic nerve crush (ONC). Topical ripasudil suppressed ONC-induced phosphorylation o...
Autores principales: | Nishijima, Euido, Namekata, Kazuhiko, Kimura, Atsuko, Guo, Xiaoli, Harada, Chikako, Noro, Takahiko, Nakano, Tadashi, Harada, Takayuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515881/ https://www.ncbi.nlm.nih.gov/pubmed/32973242 http://dx.doi.org/10.1038/s41598-020-72748-3 |
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