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The neuropathic phenotype of the K/BxN transgenic mouse with spontaneous arthritis: pain, nerve sprouting and joint remodeling

The adult K/BxN transgenic mouse develops spontaneous autoimmune arthritis with joint remodeling and profound bone loss. We report that both males and females display a severe sustained tactile allodynia which is reduced by gabapentin but not the potent cyclooxygenase inhibitor ketorolac. In dorsal...

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Detalles Bibliográficos
Autores principales: Gonçalves dos Santos, Gilson, Jimenéz-Andrade, Juan Miguel, Woller, Sarah A., Muñoz-Islas, Enriqueta, Ramírez-Rosas, Martha Beatriz, Ohashi, Nobuko, Ferreira Catroli, Glaucilene, Fujita, Yuya, Yaksh, Tony L., Corr, Maripat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515905/
https://www.ncbi.nlm.nih.gov/pubmed/32973194
http://dx.doi.org/10.1038/s41598-020-72441-5