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The neuropathic phenotype of the K/BxN transgenic mouse with spontaneous arthritis: pain, nerve sprouting and joint remodeling
The adult K/BxN transgenic mouse develops spontaneous autoimmune arthritis with joint remodeling and profound bone loss. We report that both males and females display a severe sustained tactile allodynia which is reduced by gabapentin but not the potent cyclooxygenase inhibitor ketorolac. In dorsal...
Autores principales: | Gonçalves dos Santos, Gilson, Jimenéz-Andrade, Juan Miguel, Woller, Sarah A., Muñoz-Islas, Enriqueta, Ramírez-Rosas, Martha Beatriz, Ohashi, Nobuko, Ferreira Catroli, Glaucilene, Fujita, Yuya, Yaksh, Tony L., Corr, Maripat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515905/ https://www.ncbi.nlm.nih.gov/pubmed/32973194 http://dx.doi.org/10.1038/s41598-020-72441-5 |
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