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HDAC Inhibitor LBH589 Suppresses the Proliferation but Enhances the Antileukemic Effect of Human γδT Cells

γδT cells have potent effects on hematological malignancies, and their functions can be regulated by anti-tumor agents. Histone deacetylase inhibitors (HDACis) not only have antileukemic activity on leukemia but also affect immune cells during therapeutic application. In this in vitro study, we show...

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Detalles Bibliográficos
Autores principales: He, Ying, Xu, Lin, Feng, Jingjing, Wu, Kangni, Zhao, Yanmin, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515977/
https://www.ncbi.nlm.nih.gov/pubmed/33005729
http://dx.doi.org/10.1016/j.omto.2020.08.003