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The Genetic Mechanisms Driving Diversification of the KIR Gene Cluster in Primates
The activity and function of natural killer (NK) cells are modulated through the interactions of multiple receptor families, of which some recognize MHC class I molecules. The high level of MHC class I polymorphism requires their ligands either to interact with conserved epitopes, as is utilized by...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516082/ https://www.ncbi.nlm.nih.gov/pubmed/33013938 http://dx.doi.org/10.3389/fimmu.2020.582804 |