Progenitor cell niche senescence reflects pathology of the parotid salivary gland in primary Sjögren’s syndrome

OBJECTIVE: Salivary gland (SG) progenitor cells (SGPCs) maintain SG homeostasis. We have previously shown that in primary Sjögren’s syndrome (pSS), SGPCs are likely to be senescent, and may underpin SG dysfunction. This study assessed the extent of senescence of cells in a SGPC niche in pSS patients...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyan, Bootsma, Hendrika, Terpstra, Janneke, Vissink, Arjan, van der Vegt, Bert, Spijkervet, Fred K L, Kroese, Frans G M, Pringle, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516109/
https://www.ncbi.nlm.nih.gov/pubmed/32159757
http://dx.doi.org/10.1093/rheumatology/keaa012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516109/
https://www.ncbi.nlm.nih.gov/pubmed/32159757
http://dx.doi.org/10.1093/rheumatology/keaa012

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