Morpholino Oligomer-Induced Dystrophin Isoforms to Map the Functional Domains in the Dystrophin Protein

Dystrophin plays a crucial role in maintaining sarcolemma stability during muscle contractions, and mutations that prevent the expression of a functional protein cause Duchenne muscular dystrophy (DMD). Antisense oligonucleotide-mediated manipulation of pre-messenger RNA splicing to bypass Duchenne-...

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Detalles Bibliográficos
Autores principales: Li, Dunhui, Adams, Abbie M., Johnsen, Russell D., Fletcher, Susan, Wilton, Steve D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516190/
https://www.ncbi.nlm.nih.gov/pubmed/33230432
http://dx.doi.org/10.1016/j.omtn.2020.08.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516190/
https://www.ncbi.nlm.nih.gov/pubmed/33230432
http://dx.doi.org/10.1016/j.omtn.2020.08.019

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