Squalenoylated Nanoparticle Pro-Drugs of Adjuvant Antitumor 11α-Hydroxyecdysteroid 2,3-Acetonides Act as Cytoprotective Agents Against Doxorubicin and Paclitaxel

Several ecdysteroid acetonides act as adjuvant chemo-sensitizing agents against various cancer cell lines, and they can be formulated to self-assembling nanoparticle (NP) pro-drugs through a hydrolysable conjugation with squalene. In the bloodstream such squalenoylated nanoparticles dissolve into lo...

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Detalles Bibliográficos
Autores principales: Vágvölgyi, Máté, Bélteky, Péter, Bogdán, Dóra, Nové, Márta, Spengler, Gabriella, Latif, Ahmed D., Zupkó, István, Gáti, Tamás, Tóth, Gábor, Kónya, Zoltán, Hunyadi, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516204/
https://www.ncbi.nlm.nih.gov/pubmed/33013388
http://dx.doi.org/10.3389/fphar.2020.552088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516204/
https://www.ncbi.nlm.nih.gov/pubmed/33013388
http://dx.doi.org/10.3389/fphar.2020.552088

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