Galectin-3 in Prostate Cancer Stem-Like Cells Is Immunosuppressive and Drives Early Metastasis

Galectin-3 (Gal-3) is an extracellular matrix glycan-binding protein with several immunosuppressive and pro-tumor functions. The role of Galectin-3 in cancer stem-like cells (CSCs) is poorly investigated. Here, we show that prostate CSCs also colonizing prostate-draining lymph nodes of transgenic ad...

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Detalles Bibliográficos
Autores principales: Caputo, Sara, Grioni, Matteo, Brambillasca, Chiara S., Monno, Antonella, Brevi, Arianna, Freschi, Massimo, Piras, Ignazio S., Elia, Angela R., Pieri, Valentina, Baccega, Tania, Lombardo, Angelo, Galli, Rossella, Briganti, Alberto, Doglioni, Claudio, Jachetti, Elena, Bellone, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516304/
https://www.ncbi.nlm.nih.gov/pubmed/33013832
http://dx.doi.org/10.3389/fimmu.2020.01820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516304/
https://www.ncbi.nlm.nih.gov/pubmed/33013832
http://dx.doi.org/10.3389/fimmu.2020.01820

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