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Roles of OB-Fold Proteins in Replication Stress

Accurate DNA replication is essential for maintaining genome stability. However, this stability becomes vulnerable when replication fork progression is stalled or slowed – a condition known as replication stress. Prolonged fork stalling can cause DNA damage, leading to genome instabilities. Thus, ce...

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Detalles Bibliográficos
Autores principales: Nguyen, Dinh-Duc, Kim, Eugene Y., Sang, Pau Biak, Chai, Weihang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517361/
https://www.ncbi.nlm.nih.gov/pubmed/33043007
http://dx.doi.org/10.3389/fcell.2020.574466