Therapeutic Potential of Targeting Malt1-Dependent TCR Downstream Signaling to Promote the Survival of MHC-Mismatched Allografts

Strategies targeting T cells are the cornerstone of immunosuppression after solid organ transplantation. The transcription factor NF-κB is a key regulator of downstream T-cell activation and induction of inflammatory mediators; its full activation via antigen receptor engagement requires both the sc...

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Detalles Bibliográficos
Autores principales: Govender, Lerisa, Mikulic, Josip, Wyss, Jean-Christophe, Gaide, Olivier, Thome, Margot, Golshayan, Dela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517581/
https://www.ncbi.nlm.nih.gov/pubmed/33042160
http://dx.doi.org/10.3389/fimmu.2020.576651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517581/
https://www.ncbi.nlm.nih.gov/pubmed/33042160
http://dx.doi.org/10.3389/fimmu.2020.576651

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