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Computational Approaches in Preclinical Studies on Drug Discovery and Development

Because undesirable pharmacokinetics and toxicity are significant reasons for the failure of drug development in the costly late stage, it has been widely recognized that drug ADMET properties should be considered as early as possible to reduce failure rates in the clinical phase of drug discovery....

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Detalles Bibliográficos
Autores principales: Wu, Fengxu, Zhou, Yuquan, Li, Langhui, Shen, Xianhuan, Chen, Ganying, Wang, Xiaoqing, Liang, Xianyang, Tan, Mengyuan, Huang, Zunnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517894/
https://www.ncbi.nlm.nih.gov/pubmed/33062633
http://dx.doi.org/10.3389/fchem.2020.00726