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Pharmacological targeting of mitochondrial function and reactive oxygen species production prevents colon 26 cancer-induced cardiorespiratory muscle weakness

Cancer cachexia is a syndrome characterized by profound cardiac and diaphragm muscle wasting, which increase the risk of morbidity in cancer patients due to failure of the cardiorespiratory system. In this regard, muscle relies greatly on mitochondria to meet energy requirements for contraction and...

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Detalles Bibliográficos
Autores principales: Smuder, Ashley J., Roberts, Brandon M., Wiggs, Michael P., Kwon, Oh Sung, Yoo, Jeung-Ki, Christou, Demetra D., Fuller, David D., Szeto, Hazel H., Judge, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517961/
https://www.ncbi.nlm.nih.gov/pubmed/33014286
http://dx.doi.org/10.18632/oncotarget.27748