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Pharmacological targeting of mitochondrial function and reactive oxygen species production prevents colon 26 cancer-induced cardiorespiratory muscle weakness
Cancer cachexia is a syndrome characterized by profound cardiac and diaphragm muscle wasting, which increase the risk of morbidity in cancer patients due to failure of the cardiorespiratory system. In this regard, muscle relies greatly on mitochondria to meet energy requirements for contraction and...
Autores principales: | Smuder, Ashley J., Roberts, Brandon M., Wiggs, Michael P., Kwon, Oh Sung, Yoo, Jeung-Ki, Christou, Demetra D., Fuller, David D., Szeto, Hazel H., Judge, Andrew R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517961/ https://www.ncbi.nlm.nih.gov/pubmed/33014286 http://dx.doi.org/10.18632/oncotarget.27748 |
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