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Chemotherapy Controls Metastasis Through Stimulatory Effects on GRP78 and Its Transcription Factor CREB3L1

To achieve a cure for metastatic breast cancer, further understanding of molecular drivers of the metastatic cascade is essential. Currently, chemotherapy regimens include doxorubicin and paclitaxel which act in part by inducing the unfolded protein response (UPR). The master regulator of the UPR, g...

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Detalles Bibliográficos
Autores principales: Raiter, Annat, Lipovetsky, Julia, Hyman, Lucila, Mugami, Shany, Ben-Zur, Tali, Yerushalmi, Rinat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518037/
https://www.ncbi.nlm.nih.gov/pubmed/33042795
http://dx.doi.org/10.3389/fonc.2020.01500