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Therapeutic Cytokine Inhibition Modulates Activation and Homing Receptors of Peripheral Memory B Cell Subsets in Rheumatoid Arthritis Patients

Memory B cells have known to play an important role in the pathogenesis of rheumatoid arthritis (RA). With the emergence of B cell-targeted therapies, the modulation of memory B cells appears to be a key therapeutic target. Human peripheral memory B cells can be distinguished based on the phenotypic...

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Detalles Bibliográficos
Autores principales: Mahmood, Zafar, Schmalzing, Marc, Dörner, Thomas, Tony, Hans-Peter, Muhammad, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518039/
https://www.ncbi.nlm.nih.gov/pubmed/33042152
http://dx.doi.org/10.3389/fimmu.2020.572475