PPARγ Cistrome Repression during Activation of Lung Monocyte-Macrophages in Severe COVID-19

The molecular mechanisms of cytokine storm in patients with severe COVID-19 infections are poorly understood. To uncover these events, we performed transcriptome analyses of lung biopsies from patients with COVID-19, revealing a gene enrichment pattern similar to that of PPARγ-knockout macrophages....

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Detalles Bibliográficos
Autores principales: Desterke, Christophe, Turhan, Ali G., Bennaceur-Griscelli, Annelise, Griscelli, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518203/
https://www.ncbi.nlm.nih.gov/pubmed/33015591
http://dx.doi.org/10.1016/j.isci.2020.101611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518203/
https://www.ncbi.nlm.nih.gov/pubmed/33015591
http://dx.doi.org/10.1016/j.isci.2020.101611

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