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PPARγ Cistrome Repression during Activation of Lung Monocyte-Macrophages in Severe COVID-19
The molecular mechanisms of cytokine storm in patients with severe COVID-19 infections are poorly understood. To uncover these events, we performed transcriptome analyses of lung biopsies from patients with COVID-19, revealing a gene enrichment pattern similar to that of PPARγ-knockout macrophages....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518203/ https://www.ncbi.nlm.nih.gov/pubmed/33015591 http://dx.doi.org/10.1016/j.isci.2020.101611 |