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Delayed alveolar bone repair and osteonecrosis associated with Zoledronic Acid therapy in rats: macroscopic, microscopic and molecular analysis

OBJECTIVE: This study aims to evaluate bone repair and the development of the medication related osteonecrosis of the jaw (MRONJ) associated with the use of zoledronic acid in Wistar rats. METHODOLOGY: 48 male Wistar rats were divided into four groups: ZA, treated with intraperitoneal zoledronic aci...

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Detalles Bibliográficos
Autores principales: FERREIRA, Gustavo Zanna, ZEN, Edson Virgílio, RUBIRA-BULLEN, Izabel Regina Fisher, GARLET, Gustavo Pompermaier, SANTOS, Carlos Ferreira, SANTOS, Paulo Sérgio da Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade De Odontologia De Bauru - USP 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518245/
https://www.ncbi.nlm.nih.gov/pubmed/32997086
http://dx.doi.org/10.1590/1678-7757-2020-0204