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Multi-omics analysis identifies FoxO1 as a regulator of macrophage function through metabolic reprogramming

Macrophages are plastic cells that can switch among different states according to bioenergetic or biosynthetic requirements. Our previous work demonstrated that the transcription factor Forkhead Box Protein 1 (FoxO1) plays a pivotal role in regulating the function of macrophages, but the underlying...

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Detalles Bibliográficos
Autores principales: Yan, Kai, Da, Tian-Tian, Bian, Zhen-Hua, He, Yi, Liu, Meng-Chu, Liu, Qing-Zhi, Long, Jie, Li, Liang, Gao, Cai-Yue, Yang, Shu-Han, Zhao, Zhi-Bin, Lian, Zhe-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518254/
https://www.ncbi.nlm.nih.gov/pubmed/32973162
http://dx.doi.org/10.1038/s41419-020-02982-0