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Multi-omics analysis identifies FoxO1 as a regulator of macrophage function through metabolic reprogramming
Macrophages are plastic cells that can switch among different states according to bioenergetic or biosynthetic requirements. Our previous work demonstrated that the transcription factor Forkhead Box Protein 1 (FoxO1) plays a pivotal role in regulating the function of macrophages, but the underlying...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518254/ https://www.ncbi.nlm.nih.gov/pubmed/32973162 http://dx.doi.org/10.1038/s41419-020-02982-0 |