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Sodium nitrate co-supplementation does not exacerbate low dose metronomic doxorubicin-induced cachexia in healthy mice

The purpose of this study was to determine whether (1) sodium nitrate (SN) treatment progressed or alleviated doxorubicin (DOX)-induced cachexia and muscle wasting; and (2) if a more-clinically relevant low-dose metronomic (LDM) DOX treatment regimen compared to the high dosage bolus commonly used i...

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Detalles Bibliográficos
Autores principales: Campelj, Dean G., Debruin, Danielle A., Timpani, Cara A., Hayes, Alan, Goodman, Craig A., Rybalka, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518269/
https://www.ncbi.nlm.nih.gov/pubmed/32973229
http://dx.doi.org/10.1038/s41598-020-71974-z