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Purified Sika deer antler protein attenuates GM-induced nephrotoxicity by activating Nrf2 pathway and inhibiting NF-κB pathway

Although gentamicin is widely used as an antibiotic in clinical practice, it also has some side-effects, such as acute kidney injury, which is a common condition caused by the abuse of gentamicin. Sika deer antler protein (SDAPR) can antagonize drug-induced AKI. Since SDAPR is recognized as an effec...

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Detalles Bibliográficos
Autores principales: Wang, Zhenyi, Wang, Lulu, Wang, Jing, Luo, Jiacheng, Ruan, Haonan, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518274/
https://www.ncbi.nlm.nih.gov/pubmed/32973191
http://dx.doi.org/10.1038/s41598-020-71943-6