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Generation of myostatin edited horse embryos using CRISPR/Cas9 technology and somatic cell nuclear transfer
The application of new technologies for gene editing in horses may allow the generation of improved sportive individuals. Here, we aimed to knock out the myostatin gene (MSTN), a negative regulator of muscle mass development, using CRISPR/Cas9 and to generate edited embryos for the first time in hor...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518276/ https://www.ncbi.nlm.nih.gov/pubmed/32973188 http://dx.doi.org/10.1038/s41598-020-72040-4 |