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Generation of myostatin edited horse embryos using CRISPR/Cas9 technology and somatic cell nuclear transfer

The application of new technologies for gene editing in horses may allow the generation of improved sportive individuals. Here, we aimed to knock out the myostatin gene (MSTN), a negative regulator of muscle mass development, using CRISPR/Cas9 and to generate edited embryos for the first time in hor...

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Detalles Bibliográficos
Autores principales: Moro, Lucia Natalia, Viale, Diego Luis, Bastón, Juan Ignacio, Arnold, Victoria, Suvá, Mariana, Wiedenmann, Elisabet, Olguín, Martín, Miriuka, Santiago, Vichera, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518276/
https://www.ncbi.nlm.nih.gov/pubmed/32973188
http://dx.doi.org/10.1038/s41598-020-72040-4