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High glucose alters the DNA methylation pattern of neurodevelopment associated genes in human neural progenitor cells in vitro
Maternal diabetes alters the global epigenetic mechanisms and expression of genes involved in neural tube development in mouse embryos. Since DNA methylation is a critical epigenetic mechanism that regulates gene functions, gene-specific DNA methylation alterations were estimated in human neural pro...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518427/ https://www.ncbi.nlm.nih.gov/pubmed/32973238 http://dx.doi.org/10.1038/s41598-020-72485-7 |