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High glucose alters the DNA methylation pattern of neurodevelopment associated genes in human neural progenitor cells in vitro

Maternal diabetes alters the global epigenetic mechanisms and expression of genes involved in neural tube development in mouse embryos. Since DNA methylation is a critical epigenetic mechanism that regulates gene functions, gene-specific DNA methylation alterations were estimated in human neural pro...

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Detalles Bibliográficos
Autores principales:	Kandilya, Deepika, Shyamasundar, Sukanya, Singh, Dhiraj Kumar, Banik, Avijit, Hande, Manoor Prakash, Stünkel, Walter, Chong, Yap Seng, Dheen, S. Thameem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518427/ https://www.ncbi.nlm.nih.gov/pubmed/32973238 http://dx.doi.org/10.1038/s41598-020-72485-7

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