Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells

Non-invasively probing metabolites within single live cells is highly desired but challenging. Here we utilize Raman spectro-microscopy for spatial mapping of metabolites within single cells, with the specific goal of identifying druggable metabolic susceptibilities from a series of patient-derived...

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Detalles Bibliográficos
Autores principales: Du, Jiajun, Su, Yapeng, Qian, Chenxi, Yuan, Dan, Miao, Kun, Lee, Dongkwan, Ng, Alphonsus H. C., Wijker, Reto S., Ribas, Antoni, Levine, Raphael D., Heath, James R., Wei, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518429/
https://www.ncbi.nlm.nih.gov/pubmed/32973134
http://dx.doi.org/10.1038/s41467-020-18376-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518429/
https://www.ncbi.nlm.nih.gov/pubmed/32973134
http://dx.doi.org/10.1038/s41467-020-18376-x

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