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SET/TAF1 forms a distance-dependent feedback loop with Aurora B and Bub1 as a tension sensor at centromeres

During mitosis, spatiotemporal regulation of phosphorylation at the kinetochore is essential for accurate chromosome alignment and proper chromosome segregation. Aurora B kinase phosphorylates kinetochore substrates to correct improper kinetochore-microtubule (KT-MT) attachments, whereas tension acr...

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Detalles Bibliográficos
Autores principales: Asai, Yuichiro, Matsumura, Rieko, Hasumi, Yurina, Susumu, Hiroaki, Nagata, Kyosuke, Watanabe, Yoshinori, Terada, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518443/
https://www.ncbi.nlm.nih.gov/pubmed/32973131
http://dx.doi.org/10.1038/s41598-020-71955-2