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An Optimized Protocol for In Vivo Analysis of Tumor Cell Division in a Sleeping Beauty-Mediated Mouse Glioma Model

Malignant gliomas are the most common and aggressive primary brain tumor in adults, and high mitotic rates are associated with their malignancy. Gliomas were modeled in mice using the Sleeping Beauty system to encode genetic lesions recapitulating the human disease. The presented workflow allows the...

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Detalles Bibliográficos
Autores principales: Garcia-Fabiani, Maria B., Kadiyala, Padma, Lowenstein, Pedro R., Castro, Maria G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518519/
https://www.ncbi.nlm.nih.gov/pubmed/32984853
http://dx.doi.org/10.1016/j.xpro.2020.100044