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An Optimized Protocol for In Vivo Analysis of Tumor Cell Division in a Sleeping Beauty-Mediated Mouse Glioma Model
Malignant gliomas are the most common and aggressive primary brain tumor in adults, and high mitotic rates are associated with their malignancy. Gliomas were modeled in mice using the Sleeping Beauty system to encode genetic lesions recapitulating the human disease. The presented workflow allows the...
Autores principales: | Garcia-Fabiani, Maria B., Kadiyala, Padma, Lowenstein, Pedro R., Castro, Maria G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518519/ https://www.ncbi.nlm.nih.gov/pubmed/32984853 http://dx.doi.org/10.1016/j.xpro.2020.100044 |
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