Cyclosporine Broadens the Therapeutic Potential of Lenalidomide in Myeloid Malignancies

The immunomodulatory drug lenalidomide is used for the treatment of certain hematologic malignancies, including myelodysplastic syndromes (MDS). Lenalidomide interacts with cereblon (CRBN), a component of the CRL4(CRBN) E3 ubiquitin ligase complex, leading to ubiquitination and subsequent degradatio...

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Detalles Bibliográficos
Autores principales: Dou, Aixia, Fang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518522/
https://www.ncbi.nlm.nih.gov/pubmed/32984863
http://dx.doi.org/10.33696/immunology.2.049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518522/
https://www.ncbi.nlm.nih.gov/pubmed/32984863
http://dx.doi.org/10.33696/immunology.2.049

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