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Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental models

Schistosomiasis control is heavily reliant on the drug praziquantel (PZQ), which is used as preventive chemotherapy as part of national helminth control strategies. Given the heavy reliance on PZQ for mass drug administration, there has been considerable research on the potential of parasites develo...

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Detalles Bibliográficos
Autores principales: Zdesenko, Grace, Mutapi, Francisca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518612/
https://www.ncbi.nlm.nih.gov/pubmed/32976496
http://dx.doi.org/10.1371/journal.pntd.0008649