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Developmental and social deficits and enhanced sensitivity to prenatal chlorpyrifos in PON1(-/-) mouse pups and adults
The levels and activity of the enzyme paraoxonase 1 affect the vulnerability to the teratogenic effects of organophosphate pesticides. Mutant mice lacking the gene for paraoxonase1 (PON1(-/-)) are more susceptible to the toxic effects of chlorpyrifos, and were hypothesized to be more vulnerable to s...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518626/ https://www.ncbi.nlm.nih.gov/pubmed/32976529 http://dx.doi.org/10.1371/journal.pone.0239738 |